Boost your Drug Discovery
with organelles
Oria Bioscience is a pionnering French TechBio company, expert in generating organelles.
For the first time, access organelles compatible with pharmaceutical requirements in terms of volume (HTS compatible), quality and stability.
Shift your focus from cells to organelles to catch cutting-edge therapeutics opportunities.
We purify high quality organelles in microfluidics with a unique patented process developed at ENS Paris - CNRS.
Work at organelle scale to develop your next First-in-Class molecule
Improve your Hit-to-Lead and Lead Optimization selectivity with organelle based-screening
Conduct you high throughput screening on ready-to-use lysosomes
De-risk your assets and grow your pipeline by testing your mechanism of action on organelles
Conduct your research with unlimited and high-quality organelles
Dysfunctions in cellular organelles can trigger numerous neurodegenerative diseases, rare diseases, cardiovascular diseases, cancers...
Lysosomes act as the recycling centers of cells, breaking down waste materials and cellular debris. Dysfunctions in the lysosome can generate diseases such as neurodegenerative disorders (Alzheimer’s, Parkinson’s…), as well as certain types of cancers.
TARGETS
TMEM175, TRPML1, ATP13A2...
Mitochondria are the powerhouses of cells, generating the energy required for cellular functions. Dysfunctions in mitochondria can lead to various diseases, including metabolic disorders and certain types of muscular and neurological conditions.
TARGETS
MCU, IMAC, NRS2...
The endoplasmic reticulum is crucial for protein and lipid synthesis, as well as the detoxification of chemicals within cells. Dysfunctions in the reticulum can cause diseases such as diabetes, liver disease, and neurodegenerative disorders.
TARGETS
IP3R, SERCA, RYR...
Receive your HEK-lysosomes from our in house cell-lines. Our Lyso-Prep is compatible with you screening platform, they can be native or with an overexpressed target.
Receive your lysosomal preparations from your own HEK-cell lines
Work in collaboration on new cell-lines, new organelles or new targets
At Oria Bioscience, we forge strong, personalized partnerships to advance organelle research. Our team is committed to using its expertise to deliver high-quality solutions that will significantly enhance your success and innovation.
Experience unparalleled support and expertise in organelle research
Access high quality and reliable solutions designed for your specific R&D projects.
Collaborate with industry-leading scientists and researchers to achieve groundbreaking results
With a diverse range of skills and extensive experience, we are committed to advancing scientific discoveries and delivering groundbreaking solutions
Find answers to common questions about our product, services, technologies, and how Oria Bioscience can support your research needs.
Oria Bioscience offers batches of purified organelles from HEK-cells, overexpressing the targets you need.
Oria Bioscience can purify organelles from your own cell lines. It will include a additionnal R&D service fee.
Oria's smooth purification precess prevserve the integrity of the organelle and the activity of the various proteins (ion channels, transporters, enzymes...). The functionality can be preserve up to 21 days and can be sent worldwide.
